Incorporating Flow Limitation Into the Diagnosis and Quantification of Sleep Disordered Breathing

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Brief Summary

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The diagnosis and treatment of sleep disordered breathing have come to the forefront of clinical medicine following recognition of the high prevalence and associated morbidity of sleep apnea. The effects on quality of life as well as societal costs have been well documented. The NYU Sleep Research Laboratory has spent the last several years working on the problem of improving the diagnosis of mild sleep disordered breathing which manifests as the upper airway resistance syndrome. Our approach has been to develop a non-invasive technique to detect increased upper airway resistance directly from analysis of the airflow signal. A characteristic intermittent change of the inspiratory flow contour, which is indicative of the occurrence of flow limitation, correlates well with increased airway resistance.

Currently all respiratory events are identified manually and totaled. This is time consuming and subject to variability. The objective of the present project is to improve upon the manual approach by implementing an artificially intelligent system for the identification and quantification of sleep disordered breathing based solely on non-invasive cardiopulmonary signals collected during a routine sleep study. The utility of other reported indices of sleep disordered breathing obtained during a sleep study will be evaluated.

Successful development of an automated system that can identify and classify upper airway resistance events will simplify, standardize and improve the diagnosis of sleep disordered breathing, and greatly facilitate research and clinical work in this area. Using a physiological based determination of disease should allow better assessment of treatment responses in mild disease.

Detailed Description

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Conditions

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Sleep-Disordered Breathing

Study Design

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Primary Study Purpose

DIAGNOSTIC

Interventions

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Non-invasive technique to diagnose and quantitate sleep-disordered breathing

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with sleep disordered breathing

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Locations

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NYU Sleep Disorders Center

New York, New York, United States

Site Status

Countries

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United States

Other Identifiers

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M01RR000096

Identifier Type: NIH

Identifier Source: secondary_id

View Link

NCRR-M01RR00096-0938

Identifier Type: -

Identifier Source: org_study_id