Ultraviolet Light Therapy for Systemic Lupus Erythematosus

NCT ID: NCT00004375

Last Updated: 2005-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

1991-09-30

Brief Summary

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OBJECTIVES:

I. Evaluate the mechanisms of ultraviolet A-1 light therapy in patients with systemic lupus erythematosus and normal controls.

Detailed Description

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PROTOCOL OUTLINE:

Treatment with ultraviolet A-1 light is administered 5 days a week for 6 weeks, at the lowest dose or frequency required to maintain a response. The dose and frequency are progressively decreased over the next 9 weeks.

Conditions

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Systemic Lupus Erythematosus

Study Design

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Primary Study Purpose

TREATMENT

Interventions

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ultraviolet A-1 light treatment

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

PROTOCOL ENTRY CRITERIA:

--Disease Characteristics--

Patients ages 15 to 70 with symptomatic systemic lupus erythematosus meeting American Rheumatism Association criteria and normal controls

--Prior/Concurrent Therapy--

No requirement for tetracycline or other photosensitizing drugs
Minimum Eligible Age

15 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Louisiana State University Health Sciences Center in New Orleans

OTHER

Sponsor Role collaborator

National Center for Research Resources (NCRR)

NIH

Sponsor Role lead

Principal Investigators

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Hugh McGrath, Jr.

Role: STUDY_CHAIR

Louisiana State University Health Sciences Center in New Orleans

Locations

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General Clinical Research Center and Charity Hospital (University of Louisiana)

New Orleans, Louisiana, United States

Site Status RECRUITING

Alton Ochsner Medical Foundation Hospital

New Orleans, Louisiana, United States

Site Status RECRUITING

Countries

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United States

Facility Contacts

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Hugh McGrath, Jr.

Role: primary

504-568-4630

Jawed Alam

Role: primary

504-842-3314

References

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McGrath H, Martinez-Osuna P, Lee FA. Ultraviolet-A1 (340-400 nm) irradiation therapy in systemic lupus erythematosus. Lupus. 1996 Aug;5(4):269-74. doi: 10.1177/096120339600500405.

Reference Type BACKGROUND
PMID: 8869897 (View on PubMed)

Other Identifiers

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LSUMC-1765

Identifier Type: -

Identifier Source: secondary_id

LSUMC-910067

Identifier Type: -

Identifier Source: secondary_id

NCRR-M01RR05096-0002

Identifier Type: -

Identifier Source: org_study_id