A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations
NCT ID: NCT00002430
Last Updated: 2005-06-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
220 participants
INTERVENTIONAL
Brief Summary
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Detailed Description
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Conditions
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Study Design
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TREATMENT
Interventions
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Indinavir sulfate
Nelfinavir mesylate
Lamivudine
Stavudine
Eligibility Criteria
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Inclusion Criteria
* Are HIV positive.
* Have a viral load (level of HIV in your blood) of at least 10,000 copies/ml within 45 days of study entry.
* Have a CD4 cell count of at least 100 cells/mm3 within 45 days of study entry.
* Have a normal chest X-ray.
* Have never taken protease inhibitors or 3TC.
* Are 16 years of age or older.
* Agree to practice sexual abstinence or use barrier methods of birth control (e.g., condoms).
Exclusion Criteria
* Have an active opportunistic (AIDS-related) infection or cancer.
* Have certain types of Kaposi's sarcoma.
* Have hepatitis.
* Have chronic diarrhea.
* Have a history of certain medical conditions.
* Are allergic to any of the study medications.
* Are taking certain medications.
* Are pregnant or breast-feeding.
16 Years
ALL
No
Sponsors
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Merck Sharp & Dohme LLC
INDUSTRY
Locations
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Univ of Alabama School of Med
Montgomery, Alabama, United States
Ocean View Internal Medicine
Long Beach, California, United States
AIDS Healthcare Foundation
Los Angeles, California, United States
Tower ID Med Associates
Los Angeles, California, United States
Oasis Clinic / King Drew Med Ctr
Los Angeles, California, United States
Robert Scott MD
Oakland, California, United States
AIDS Community Research Consortium
Redwood City, California, United States
Saint Francis Mem Hosp / HIV Care Unit
San Francisco, California, United States
Pacific Horizons Med Group
San Francisco, California, United States
Kaiser Foundation Hospital
San Francisco, California, United States
Harbor - UCLA Med Ctr
Torrance, California, United States
Denver Public Health Dept
Denver, Colorado, United States
Blick Med Associates
Stamford, Connecticut, United States
Physicans Home Service
Washington D.C., District of Columbia, United States
IDC Research Initiative
Altamonte Springs, Florida, United States
Univ of Miami School of Medicine
Miami, Florida, United States
Hillsborough County Health Dept
Tampa, Florida, United States
Emory Univ
Atlanta, Georgia, United States
Harold Katner MD
Macon, Georgia, United States
Thomas Coffman MD
Boise, Idaho, United States
Chicago Ctr for Clinical Research
Chicago, Illinois, United States
Northwestern Univ Med Ctr
Chicago, Illinois, United States
Univ of Illinois
Chicago, Illinois, United States
Kentucky Clinical Research
Lexington, Kentucky, United States
Louisiana State Univ Med Ctr / Tulane Med School
New Orleans, Louisiana, United States
AIDS Consultation Service / Maine Med Ctr
Portland, Maine, United States
Institute of Human Virology
Baltimore, Maryland, United States
JSI Research and Training Institute
Boston, Massachusetts, United States
Education & Research Building
Camden, New Jersey, United States
NJCRI
Newark, New Jersey, United States
Infectious Disease Specialists of NJ
Union, New Jersey, United States
Brookdale Univ Hosp and Med Ctr
Brooklyn, New York, United States
Liberty Med Group
New York, New York, United States
James Jones MD
New York, New York, United States
Mount Sinai Med Ctr
New York, New York, United States
Community Health Network
Rochester, New York, United States
Wake Forest Univ School of Medicine
Winston-Salem, North Carolina, United States
Associates in Med and Mental Health
Tulsa, Oklahoma, United States
The Research and Education Group
Portland, Oregon, United States
Fanno Creek Clinic
Portland, Oregon, United States
Anderson Clinical Research / Inc
Pittsburgh, Pennsylvania, United States
Burnside Clinic
Columbia, South Carolina, United States
Vanderbilt Univ Med Ctr
Nashville, Tennessee, United States
Oak Lawn Physicians Group
Dallas, Texas, United States
Univ TX Galveston Med Branch
Galveston, Texas, United States
Infections Ltd / Physicians Med Ctr
Tacoma, Washington, United States
Countries
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Other Identifiers
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079-02
Identifier Type: -
Identifier Source: secondary_id
CRX454
Identifier Type: -
Identifier Source: secondary_id
246R
Identifier Type: -
Identifier Source: org_study_id