A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection
NCT ID: NCT00002270
Last Updated: 2005-06-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
INTERVENTIONAL
Brief Summary
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Detailed Description
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Conditions
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Study Design
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TREATMENT
Interventions
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Interferon alfa-2b
Zidovudine
Eligibility Criteria
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Inclusion Criteria
* HIV seropositivity by both ELISA and Western blot.
* Biopsy proven progressive multifocal leukoencephalopathy (PML).
Exclusion Criteria
Patients with the following conditions or symptoms are excluded:
* Intolerant to interferon.
* Prior or concomitant central nervous system disease (CNS) such as toxoplasmosis, multiple sclerosis (MS), or neurosyphilis.
Patients with the following are excluded:
* Intolerant to interferon.
* Prior or concomitant central nervous system disease (CNS) such as toxoplasmosis, multiple sclerosis (MS), or neurosyphilis.
Prior Medication:
Excluded:
* Patients receiving interferon for other reasons.
18 Years
65 Years
ALL
No
Sponsors
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University of Miami
OTHER
Locations
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Univ of Miami School of Medicine
Miami, Florida, United States
Countries
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Other Identifiers
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074A
Identifier Type: -
Identifier Source: org_study_id