A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study.

NCT ID: NCT00002253

Last Updated: 2005-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Brief Summary

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The primary objective of this study is to determine the relapse rate in patients with AIDS-related diarrhea who were found to be "Responders" in a previous placebo-controlled, double-blind study of Sandostatin (Study #D203 - FDA 102A).

The secondary objectives include: 1) To evaluate clinical efficacy and safety of open-label Sandostatin in patients who were "Non-Responders" in Study #D203 - FDA 102A; 2) To evaluate the efficacy and safety of Sandostatin during prolonged open-label treatment in "Responders" from Study #D03 - FDA 102A.

Detailed Description

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Conditions

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Diarrhea HIV Infections

Study Design

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Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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Octreotide

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Patients must have the following:

* Only patients who have completed the duration of Study D203, FDA 102A will be eligible for this study.
* Each of these patients must give written informed consent to participate in Study D204, FDA 102B as well.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sandoz

INDUSTRY

Sponsor Role lead

Locations

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USC School of Medicine

Los Angeles, California, United States

Site Status

UCSD Med Ctr

San Diego, California, United States

Site Status

UCSF - San Francisco Gen Hosp

San Francisco, California, United States

Site Status

Kaiser Permanente Med Ctr

San Francisco, California, United States

Site Status

San Mateo County Gen Hosp

San Mateo, California, United States

Site Status

Med Service

Miami, Florida, United States

Site Status

Emory Univ School of Medicine

Atlanta, Georgia, United States

Site Status

Rush Presbyterian - Saint Luke's Med Ctr

Chicago, Illinois, United States

Site Status

Maine Med Ctr Med Clinics

Portland, Maine, United States

Site Status

Douglas Plesko

Boston, Massachusetts, United States

Site Status

Boston City Hosp

Boston, Massachusetts, United States

Site Status

Henry Ford Hosp

Detroit, Michigan, United States

Site Status

Univ of Missouri at Kansas City School of Medicine

Kansas City, Missouri, United States

Site Status

Mount Sinai Med Ctr

New York, New York, United States

Site Status

SUNY Stony Brook / Health Sciences Ctr

Stony Brook, New York, United States

Site Status

Portland Veterans Adm Med Ctr / Rsch & Education Grp

Portland, Oregon, United States

Site Status

Buckley Braffman Stern Med Associates

Philadelphia, Pennsylvania, United States

Site Status

Miriam Hosp / Family Healthcare Ctr at SSTAR

Providence, Rhode Island, United States

Site Status

Univ TX Galveston Med Branch

Galveston, Texas, United States

Site Status

Baylor College of Medicine

Houston, Texas, United States

Site Status

Infectious Disease Physicians Inc

Annandale, Virginia, United States

Site Status

Univ of Wisconsin School of Medicine

Madison, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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D204

Identifier Type: -

Identifier Source: secondary_id

102B

Identifier Type: -

Identifier Source: org_study_id