Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE3
INTERVENTIONAL
2007-09-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Keywords
Explore important study keywords that can help with search, categorization, and topic discovery.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PREVENTION
DOUBLE
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Estrogen
Estrogen and Progesterone
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Current estrogen use
* History of breast cancer
65 Years
FEMALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
National Institute on Aging (NIA)
NIH
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Mary Sano, PhD
Role: PRINCIPAL_INVESTIGATOR
Icahn School of Medicine at Mount Sinai
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of Alabama
Birmingham, Alabama, United States
University of California, Irvine
Irvine, California, United States
New England Center for Headache
Stamford, Connecticut, United States
Howard University
Washington D.C., District of Columbia, United States
Lee Memorial Health System
Fort Myers, Florida, United States
Mayo Clinic Jacksonville
Jacksonville, Florida, United States
Wein Center
Miami Beach, Florida, United States
West Florida Regional Medical Center
Pensacola, Florida, United States
North Broward Medical Center
Pompano Beach, Florida, United States
Tallahassee Memorial Health Center
Tallahassee, Florida, United States
St. Mary's Medical Center
West Palm Beach, Florida, United States
Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States
Neurology Group of Bergen County
Ridgewood, New Jersey, United States
Columbia University
New York, New York, United States
Cornell Medical Center, New York Presbyterian Medical Center
New York, New York, United States
New York United Hospital Medical Center
Port Chester, New York, United States
Burke Medical Research Institute
White Plains, New York, United States
Duke University Medical Center
Durham, North Carolina, United States
Clinical Pharmaceutical Trials
Tulsa, Oklahoma, United States
Butler Hospital, Rhode Island Hospital
Providence, Rhode Island, United States
Medical University of South Carolina
North Charleston, South Carolina, United States
Eastern Virginia Medical School
Norfolk, Virginia, United States
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Tang MX, Jacobs D, Stern Y, Marder K, Schofield P, Gurland B, Andrews H, Mayeux R. Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet. 1996 Aug 17;348(9025):429-32. doi: 10.1016/S0140-6736(96)03356-9.
Kawas C, Resnick S, Morrison A, Brookmeyer R, Corrada M, Zonderman A, Bacal C, Lingle DD, Metter E. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging. Neurology. 1997 Jun;48(6):1517-21. doi: 10.1212/wnl.48.6.1517.
Jacobs DM, Tang MX, Stern Y, Sano M, Marder K, Bell KL, Schofield P, Dooneief G, Gurland B, Mayeux R. Cognitive function in nondemented older women who took estrogen after menopause. Neurology. 1998 Feb;50(2):368-73. doi: 10.1212/wnl.50.2.368.
Aloysi A, Van Dyk K, Sano M. Women's cognitive and affective health and neuropsychiatry. Mt Sinai J Med. 2006 Nov;73(7):967-75.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
RO 1AG15922-01
Identifier Type: -
Identifier Source: secondary_id
IA0018
Identifier Type: -
Identifier Source: org_study_id